Endocrine Abstracts

Introduction: Primary amenorrhea is usually caused by either gonadal or anatomical abnormalities. Turner’s syndrome (TS) is the result of partial or complete absence of X chromosome in females with an incidence of 1 in 2500 live female births. Mullerian agenesis due to Mayer-Rokitansky-Hauser syndrome (M-R-K-H syndrome; embryonic underdevelopment of the vagina with variable uterine development) has an incidence of 1 in 5000 females and can be mistakenly diagnosed in patie...

Case presentation: A 34-year-old woman was diagnosed with hypertension from the age of 26 years. She had been investigated in Canada previously and discovered to have a small left adrenal nodule, satisfactory aldosterone and renin levels, but raised urinary free cortisol levels and non-suppressed cortisol levels on overnight 1 mg dexamethasone suppression test. Upon assessment in our service, the patient reported a history of easy bruising and insomnia. Her BMI was 28.1 kg/m&#...

Acromegaly is a rare endocrine disorder mostly caused by a growth hormone (GH)-secreting pituitary adenoma. The aim of treatment is to normalize GH/IGF1 levels to limit disease burden. Growth hormone hypersecretion is associated with an increased cancer risk; cases of Acromegaly complicated by lymphoma have been reported. We share a clinical case characterized by suboptimal treatment, potentially leading to advancing orbital lymphoma. This 49-year-old man was diagnosed with Ac...

Use of 18F-FDG-PET/CT (PET) staging for a variety of malignancies has increased in recent years. A rise in detection of incidental thyroid lesions creates a novel diagnostic challenge. We present four cases of Thyroid PET positivity.A 62-year-old lady with pulmonary adenocarcinoma on contrast CT-Thorax had diffuse thyroid PET uptake. Biochemistry revealed a self-limiting TSH rise. Thyroid ultrasound showed benign nodular goitre (U2). Findin...

Use of 18F-FDG-PET/CT (PET) staging for a variety of malignancies has increased in recent years. A rise in detection of incidental thyroid lesions creates a novel diagnostic challenge. We present four cases of Thyroid PET positivity.A 62-year-old lady with pulmonary adenocarcinoma on contrast CT-Thorax had diffuse thyroid PET uptake. Biochemistry revealed a self-limiting TSH rise. Thyroid ultrasound showed benign nodular goitre (U2). Findin...